Investors & Partners at ARCH Venture Partners

Clinton Bybee

Co-Founder and Managing Director Emeritus, ARCH Venture Partners

Clinton Bybee is Co-Founder and Managing Director Emeritus at ARCH Venture Partners, a leading venture capital firm focused on early-stage innovation across multiple sectors. With deep expertise in biotech, digital health, artificial intelligence, and deeptech, Bybee has built a distinguished career identifying and supporting transformative technologies and founding teams. His role as Co-Founder at ARCH reflects his foundational contributions to establishing the firm's investment thesis and operational excellence. Through his tenure at ARCH Venture Partners, Bybee has developed a reputation for backing ambitious entrepreneurs pursuing breakthrough solutions at the intersection of science, technology, and healthcare. His investment focus spans companies leveraging cutting-edge science and engineering to solve complex real-world challenges. As Managing Director Emeritus, Bybee continues to contribute his strategic insights and industry relationships to the firm's portfolio and deal flow.

Kristina Burow

Managing Director, ARCH Venture Partners

Kristina Burow is a Managing Director at ARCH Venture Partners, a leading venture capital firm focused on early-stage scientific innovation and deep technology. At ARCH, she invests across biotech, digital health, artificial intelligence, and deeptech sectors, where she identifies and supports transformative companies addressing critical challenges in healthcare and technology. With her strategic focus on science-driven ventures, Burow works closely with founding teams to scale technologies from laboratory to market impact. Her investment thesis emphasizes backing entrepreneurs who combine rigorous scientific foundations with practical applications. Through her role at ARCH, she contributes to the firm's mission of backing the next generation of breakthrough companies that leverage cutting-edge research and engineering to create lasting value.

Mark McDonnell

Managing Director, ARCH Venture Partners

Mark McDonnell is a Managing Director at ARCH Venture Partners, a leading venture capital firm focused on early-stage scientific innovation. He invests across biotech, digital health, artificial intelligence, and deeptech sectors, identifying transformative technologies poised to create significant impact. At ARCH, McDonnell leverages deep expertise in emerging scientific domains to support founding teams in translating cutting-edge research into scalable businesses. His investment thesis centers on companies addressing fundamental challenges in healthcare and technology through novel scientific approaches. McDonnell is actively involved in sourcing, diligencing, and supporting portfolio companies through their critical early stages. His focus on converging scientific disciplines—from biotechnology to AI—reflects ARCH's commitment to backing the most ambitious technical founders and breakthrough technologies that define the next generation of innovation.

Paul Berns

Managing Director, ARCH Venture Partners

Paul Berns is a Managing Director at ARCH Venture Partners, a leading venture capital firm focused on early-stage scientific innovation and deep technology. At ARCH, Paul invests across biotech, digital health, artificial intelligence, and deeptech sectors, leveraging his expertise to identify and support transformative companies at the intersection of science and technology. His investment thesis centers on backing entrepreneurs and scientific founders who are building breakthrough solutions to address significant global challenges. As a Managing Director, Paul plays a key role in ARCH's investment strategy, deal sourcing, and portfolio company support, working closely with founding teams to accelerate their path to impact. His focus on biotech and deeptech reflects a commitment to funding ventures that push the boundaries of what's scientifically possible while creating meaningful commercial value.

Robert Nelsen

Co-Founder and Managing Director, ARCH Venture Partners

Robert Nelsen co-founded ARCH Venture Partners to commercialize deep-science ideas from universities and national labs very early, often helping create companies from the lab bench up rather than just funding existing startups. He has a dual background in biology and economics that he uses to identify which nascent scientific ideas can become large companies, and he's known for getting involved extremely early—often before ideas appear in conferences—and pairing that science with experienced repeat executives.

Steve Gillis

Managing Director, ARCH Venture Partners

Steve Gillis is a Managing Director at ARCH Venture Partners, a leading venture capital firm focused on early-stage scientific innovation and deep technology development. With a strategic investment focus spanning biotech, digital health, artificial intelligence, and deeptech sectors, Gillis brings significant expertise in identifying and scaling transformative technologies. At ARCH, he works with founding teams to commercialize breakthrough scientific discoveries and build category-defining companies. His investment philosophy emphasizes backing ventures that leverage cutting-edge science and engineering to solve complex problems across healthcare and technology domains. Gillis is actively engaged in the innovation ecosystem, connecting entrepreneurs, researchers, and industry leaders to accelerate the development of next-generation solutions. His career reflects a commitment to advancing scientific progress through venture capital investment and strategic partnership.