
Current Firm
.406 Ventures Fund
Focus
Digital Health, Cybersecurity
Maria Cirino is a serial founder-operator who scaled i-Cube from ~$5M to a $50M run rate through an IPO, then co-founded security company Guardent and sold it to VeriSign for ~$142M, giving her unusually deep credibility with technical founders compared to most VCs. At .406 Ventures, she focuses on enterprise IT, security, infrastructure, and digital health investments, bringing an operational mindset and apprenticeship model to help founders position and sell deeply technical products that are difficult for generalist VCs to underwrite.
Maria Cirino is a Founding Managing Partner, .406 Ventures Fund at .406 Ventures Fund, based in Boston, MA.
Maria's investment focus spans Digital Health, Cybersecurity, AI, Enterprise, primarily investing at the Seed, Series B+ stages. This specialization allows for deep domain knowledge and strong network effects that benefit portfolio companies.
Maria Cirino is a Founding Managing Partner, .406 Ventures Fund at .406 Ventures Fund, based in Boston, MA. Their investment focus includes Digital Health, Cybersecurity, AI.
Maria Cirino focuses on investments in Digital Health, Cybersecurity, AI, Enterprise through .406 Ventures Fund. These focus areas reflect their domain expertise and the types of startups they actively seek to back.
Maria Cirino is currently at .406 Ventures Fund, headquartered in Boston, MA, serving as Founding Managing Partner, .406 Ventures Fund.