Third Rock Ventures
UnclaimedAt a Glance
- Check Size
- $100K – $5M
- Stage
- Seed, Series A
- AUM
- $4.4B
- Sectors
- Biotech
- Founded
- 2007
- HQ
- Boston, MA
About Third Rock Ventures
Third Rock Ventures is a venture capital firm based in Boston, MA founded in 2007. Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to… The firm focuses on Seed, Series A investments across sectors including Biotech. The firm manages $3B in assets under management. Notable portfolio companies include Foundation Medicine, Syros Pharmaceuticals, Editas Medicine, Bluebird Bio, Blueprint Medicines and Karuna Therapeutics. Creates and builds breakthrough biopharmaceutical companies by combining cutting-edge science with experienced drug development teams.
Investment Thesis
“Creates and builds breakthrough biopharmaceutical companies by combining cutting-edge science with experienced drug development teams.”
Sector Focus
Investment Stage
Notable Portfolio Companies
Foundation Medicine
Editas MedicineFund History
Three former Millennium Pharmaceuticals executives, Mark Levin, Kevin Starr and Robert Tepper, started Third Rock Ventures in 2007 and closed a $378 million first fund within ten weeks. The Boston partnership has raised on a roughly three-year cadence ever since.
Third Rock Ventures II filed in April 2010 against a $400 million target. Fund III closed at $500 million with a first sale on March 15, 2013. Fund IV closed at $600 million on October 28, 2016. Fund V closed at $750 million on May 23, 2019. Fund VI, the firm's largest, closed at $1.105 billion with a first sale on May 26, 2022. Fund VII filed on June 3, 2026 targeting $750 million. Cumulative commitments across the seven partnerships exceed $4.4 billion. The capital funds a company-creation model rather than a syndicate strategy: the firm incubates biotech companies in-house, seeds them with its own partners as interim operators, and holds unusually high ownership through the first financings, which is why its fund sizes run large relative to the number of positions.
SEC Fund Filings
- Vehicles filed, last 24 months
- 1
- Latest filing
Third Rock Ventures filed a Form D for 1 fund vehicle between Sep 26, 2024 and Sep 25, 2026.
| Fund vehicle | Source |
|---|---|
| Third Rock Ventures VII, L.P. | SEC Form D, filed |
A Form D is the notice a fund files with the SEC when it raises money in a private offering. Feeder funds, parallel funds and SPVs each file their own, so the count measures filing activity, not the number of flagship funds.
Source: SEC EDGAR Form D filings for pooled investment funds, original filings only (amendments excluded). Our filing data starts Jul 1, 2024. Vehicles are matched to Third Rock Ventures by fund name and checked against the sponsor address and named principals on each filing; offering amounts are not shown. Each “SEC Form D” link opens an EDGAR full-text search for that vehicle’s exact name, where the filing itself is listed. See every new fund filing on the Form D Radar.
Team (2)
Related Articles (2)
Frequently Asked Questions
What stage does Third Rock Ventures invest at?
Third Rock Ventures primarily invests at the Seed, Series A stages. This means they focus on companies that are building their initial product and finding product-market fit.
Where is Third Rock Ventures located?
Third Rock Ventures is headquartered in Boston, MA. Many of their portfolio companies are also based in this region, though they invest across geographies.
What sectors does Third Rock Ventures focus on?
Third Rock Ventures focuses on investments in Biotech. Their portfolio reflects deep expertise and networks within these sectors.
What is Third Rock Ventures's typical check size?
Third Rock Ventures's typical investment check size ranges from $100K to $5M. Actual amounts may vary based on the stage, sector, and specific opportunity.
How much does Third Rock Ventures have under management?
Third Rock Ventures manages approximately $4.4B in assets under management (AUM) across their funds.
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