🧬 VC Directory
79 Biotech VC Firms
79 venture capital firms investing in Biotech. Browse investor profiles, investment stages, check sizes and portfolio companies.
Biotech venture works differently from the rest of this directory and the list should be read on its own terms. Rounds are larger, they are milestone-driven rather than revenue-driven, the syndicate matters more than the lead's brand, and a meaningful share of these firms create companies rather than only fund them.
The dedicated life-sciences investors here include 5AM Ventures, Atlas Venture, Venrock Healthcare, PureTech Health, Hatteras Venture Partners and Flare Capital Partners. Several run a venture-creation model in which the firm's own scientists and entrepreneurs build the company around a piece of science, often before a founding team exists, which changes what a first conversation looks like: the firm is evaluating the asset and the mechanism, not a pitch.
A second group sits at the boundary between biology and computation. Andreessen Horowitz Bio + Health, Air Street Capital, Compound, AIX Ventures and Third Culture Capital back companies applying machine learning to protein design, target identification and trial design. Playground Global and Future Ventures reach the sector through deep tech. On the agricultural and industrial side, Finistere Ventures, AgFunder and Cultivian Sandbox Ventures invest in biology applied outside human health.
Geography is concentrated. Boston and Cambridge, the Bay Area, San Diego and the Research Triangle account for most of the firms on this page, and the concentration is a function of where the research and the experienced drug-development operators are.
How to use this list. Match on modality and stage before anything else: a firm that does small molecules at Series A is not a seed investor in diagnostics, however adjacent the two look on a website. Read the portfolio and the team listing on each profile to find the partner who has run your specific development path, and expect the introduction to matter more here than in software, because these syndicates are built on long professional relationships. Each profile carries stage focus, sector focus, check size where disclosed, and fund history.
79 firms
Top Biotech firms in this list
- 3CC | Third Culture Capital · Boston, MA · Pre-Seed to Series B+ · Digital Health
- ARCH Venture Partners · Chicago, IL · Seed to Series A · Biotech
- Acequia Capital (AceCap) · Seattle, WA · Pre-Seed to Series B+ · AI
- Acre Venture Partners · San Francisco, CA · Seed to Series B+ · Agriculture
- AgFunder · San Francisco, CA · Pre-Seed to Series B+ · Agriculture
- Air Street Capital · London, UK · Seed to Series A · AI
- Andreessen Horowitz · Menlo Park, CA · Seed to Series B+ · AI
- Andreessen Horowitz Bio + Health · Menlo Park, CA · Seed to Series B+ · Biotech
- Artis Ventures (AV) · San Francisco, CA · Pre-Seed to Series B+ · Digital Health
- Canaan Partners · Westport, CT · Seed to Series A · Biotech
- Civilization Ventures · Tiburon, CA · Pre-Seed to Series B+ · Digital Health
- Contrary · San Francisco, CA · Pre-Seed to Series A · AI
- Cultivian Sandbox Ventures · Chicago, IL · Pre-Seed to Series B+ · Agriculture
- DCVC · San Francisco, CA · Seed to Series A · Deeptech
- Decheng Capital · Menlo Park, CA · Pre-Seed to Series B+ · Biotech
- Dolby Family Ventures · San Francisco, CA · Pre-Seed to Series B+ · Biotech
- E1 Ventures · Pre-Seed to Series B+ · AI
- F-Prime Capital · Cambridge, MA · Seed to Series B+ · Biotech
- FPV Ventures · San Francisco, CA · Pre-Seed to Series B+ · Enterprise
- FemHealth Ventures · Short Hills, NJ · Pre-Seed to Series B+ · Digital Health
2048 Ventures
New York, NYPre-seed firm guaranteeing funds in 10 business days.
3CC | Third Culture Capital
Boston, MALearn which startups 3CC | Third Culture Capital invests in, what size check sizes they write, and who their partners are (e.g. Julien Pham).
5AM Ventures
San Francisco, CAEarly-stage life sciences with 4:59 Initiative model.
8VC
Austin, TXActs as VC and venture studio co-founding startups with 25-30% capital allocation.
AIX Ventures
San Francisco, CALed by active AI practitioners Socher, Manning, Goldbloom.
ARCH Venture Partners
Chicago, ILInvests at concept stage, co-founding breakthrough life sciences platforms.
AbbVie Ventures
Cambridge, MAAbbVie Ventures is the strategic venture capital arm of AbbVie, investing mainly at Seed and Series A in discovery and preclinical therapeutics companies aligned with AbbVie's R&D areas.
Acequia Capital (AceCap)
Seattle, WALearn which startups Acequia Capital (AceCap) invests in, what size check sizes they write, and who their partners are (e.g. Hank Vigil).
Acre Venture Partners
San Francisco, CAClimate-focused agrifood fund with rare food-policy expertise
AgFunder
San Francisco, CALearn which startups AgFunder invests in, what size check sizes they write, and who their partners are (e.g. Michael Dean).
Air Street Capital
London, UKFocuses exclusively on AI-first companies in technical domains.
Alexandria Venture Investments
Pasadena, CaliforniaAlexandria Venture Investments is the strategic venture arm of life science REIT Alexandria Real Estate Equities, backing seed, early and growth-stage biotech, agrifoodtech and climate companies since 1996.
Amgen Ventures
Thousand Oaks, CAAmgen Ventures is the strategic venture arm of Amgen, investing since 2004 in private biotechnology companies and venture funds aligned with Amgen's research priorities in oncology, inflammation and other areas.
Andreessen Horowitz
Menlo Park, CALeads mega-rounds for frontier-tech visions with 150+ platform team and media operations.
Andreessen Horowitz Bio + Health
Menlo Park, CADedicated bio and health fund within a16z, investing in founders applying engineering and computational approaches to biology and healthcare.
Angelini Ventures
Rome, ItalyAngelini Ventures is the Rome-based venture capital firm of Angelini Industries, investing a €300 million commitment in biotech and healthtech companies across Europe and North America.
Applied Ventures
Santa Clara, CaliforniaApplied Ventures is the Santa Clara venture capital arm of Applied Materials, a stage-agnostic deep tech investor in semiconductors, photonics, AI hardware, advanced materials and robotics startups.
Artis Ventures (AV)
San Francisco, CALearn which startups Artis Ventures (AV) invests in, what size check sizes they write, and who their partners are (e.g. Stuart Peterson).
Atlas Venture
Cambridge, MASeed and early-stage investor emphasizing biotech company creation.
Canaan Partners
Westport, CTDeliberate 60/40 tech/healthcare split with transparent partner scoring.
Carbon Silicon Ventures
Learn which startups Carbon Silicon Ventures invests in, what size check sizes they write, and who their partners are (e.g. Nish Bhat).
Civilization Ventures
Tiburon, CALearn which startups Civilization Ventures invests in, what size check sizes they write, and who their partners are (e.g. Shahram Seyedin-Noor).
Compound
San Francisco, CAContrarian n-of-1 investor across frontier sectors.
Contrary
San Francisco, CAVenture firm powered by a network of top university students and recent graduates, scouting and investing in the next generation of founders.
Correlation Ventures
San Diego, CAAnalytics-driven co-investor making rapid decisions using proprietary model.
Cultivian Sandbox Ventures
Chicago, ILLearn which startups Cultivian Sandbox Ventures invests in, what size check sizes they write, and who their partners are (e.g. Steve Engelberg).
DCVC
San Francisco, CATargets companies applying modern computation to agriculture, mining, and health.
Decheng Capital
Menlo Park, CALearn which startups Decheng Capital invests in, what size check sizes they write, and who their partners are (e.g. ).
Dolby Family Ventures
San Francisco, CALearn which startups Dolby Family Ventures invests in, what size check sizes they write, and who their partners are (e.g. Pascal Levensohn).
E1 Ventures
Learn which startups E1 Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).
E2MC Ventures
Los Angeles, CAE2MC Ventures is a Los Angeles-based early-stage venture firm specializing in the space economy, investing in satellite technology, launch services, in-space manufacturing, and the broader ecosystem of technologies enabling a multi-planetary future. The firm focuses on pre-seed and seed stage companies where its deep aerospace network and technical expertise provide the most leverage. E2MC backs founders building infrastructure for the commercial space industry and adjacent deep tech sectors.
F-Prime Capital
Cambridge, MAFidelity-backed formation engine for gene therapy and rare diseases.
FPV Ventures
San Francisco, CALearn which startups FPV Ventures invests in, what size check sizes they write, and who their partners are (e.g. Pegah Ebrahimi).
FemHealth Ventures
Short Hills, NJLearn which startups FemHealth Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).
Fifty Years
San Francisco, CAOperator-heavy team backing pre-product deep-tech moonshots.
Flagship Pioneering
Cambridge, MALearn which startups Flagship Pioneering invests in, what size check sizes they write, and who their partners are (e.g. Noubar Afeyan).
Flare Capital Partners
Boston, MALearn which startups Flare Capital Partners invests in, what size check sizes they write, and who their partners are (e.g. Bill Geary).
Founders Fund
San Francisco, CAContrarian, founder-maximalist VC backing hard scientific breakthroughs.
FundersClub
San Francisco, CALearn which startups FundersClub invests in, what size check sizes they write, and who their partners are (e.g. ).
Future Ventures
San Francisco, CAInvests in purpose-driven entrepreneurs reinventing industries.
GV
Mountain View, CAGoogle's financially-driven VC with design studio and ML scoring.
Genoa Ventures
San Francisco, CALearn which startups Genoa Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).
Hatteras Venture Partners
Durham, NCLearn which startups Hatteras Venture Partners invests in, what size check sizes they write, and who their partners are (e.g. ).
Innovation Endeavors
Palo Alto, CAFounded by Eric Schmidt; invests in sensors, ML, and robotics.
Julian Capital
San Francisco, CADeeptech seed fund investing across chips, chemicals, energy, robotics.
Kaiser Permanente Ventures
Oakland, CAKaiser Permanente Ventures is the strategic venture arm of Kaiser Permanente, investing in healthcare IT, care delivery services, diagnostics and therapeutics companies that address needs in healthcare delivery.
KittyHawk Ventures
Santa Monica, CAKittyHawk Ventures is a New York-based venture firm that invests across the capital stack, from frontier seed rounds all the way through pre-IPO growth equity, focusing on transformative technology companies in sectors including fintech, enterprise software, and aerospace. The firm takes a flexible, stage-agnostic approach that allows it to build concentrated positions in breakout companies over multiple rounds. KittyHawk is known for its long-term partnership model and willingness to back unconventional founders with bold visions.
LG Technology Ventures
Santa Clara, CALG Technology Ventures is the Santa Clara venture arm of South Korea's LG Group, backing early and growth-stage companies in AI, batteries and energy, life sciences, materials and enterprise software.
Leaps by Bayer
Berlin, GermanyLeaps by Bayer is the strategic investment unit of Bayer AG, backing and forming companies that pursue fundamental breakthroughs in health and agriculture across ten defined challenges.
Lilly Ventures
Indianapolis, INLilly Ventures is Eli Lilly's global investment arm, formed in 2001, investing in early-stage biotech and novel science as one pillar of the Lilly Catalyze360 program for young drug developers.
Lux Capital
New York, NYDeep technology venture firm investing in emerging science and technology ventures in energy, healthcare, and defense.
Maverick Ventures
San Francisco, CAEvergreen fund integrated with $10B+ hedge-fund platform.
NFX
San Francisco, CASerial founder-led with Signal platform and CEO Guild network.
Novartis Venture Fund
Basel, SwitzerlandThe Novartis Venture Fund is the corporate venture arm of Novartis, investing USD 5 to 10 million at seed and Series A in therapeutics companies across North America and Europe.
OrbiMed Advisors
New York, NYHealthcare-only platform spanning seed through IPO via public/private arms.
Pfizer Ventures
New York, NYPfizer Ventures is the venture capital arm of Pfizer, investing in biotech companies in oncology, inflammation and immunology, cardiometabolic disease, vaccines and next-generation modalities.
Pillar VC
Boston, MABoston seed investor supporting professional growth.
Playground Global
Palo Alto, CADeep technology venture fund investing in AI, robotics, and synthetic biology startups with transformative potential.
Polaris Partners
Boston, MAPolaris Partners is a Boston venture capital firm founded in 1996 that invests mainly in biotechnology and healthcare companies, from company creation through later rounds. It has more than $5 billion in committed capital and runs two affiliated vehicles: the Polaris Innovation Fund for academic research and the Polaris Growth Fund for profitable, founder-owned software companies.
Prime Movers Lab
Jackson, WYDeep tech venture firm investing in breakthrough scientific startups across energy, transportation, infrastructure, and health.
Radical Ventures
Toronto, CanadaInvests in very-early to early-stage AI startups with AI research ties.
Refactor Capital
Burlingame, CASolo GP leveraging Google/Netflix/LinkedIn experience to back hard-tech.
S32 (formerly Section 32)
Palo Alto, CAS32, originally named Section 32, is a Palo Alto venture capital firm founded by Bill Maris, who started GV (Google Ventures) and ran it as CEO. S32 invests mainly at Series A and Series B in AI, computational biology, infrastructure, cybersecurity and enterprise software, manages more than $3 billion, and held a $413.5 million first close on its sixth fund in September 2025.
Sanofi Ventures
Cambridge, MASanofi Ventures is the corporate venture arm of Sanofi, investing from seed to crossover in biotech and AI and digital health companies from an evergreen fund of more than $1.4 billion.
Takeda Ventures
Cambridge, MassachusettsTakeda Ventures, Inc. is the corporate investment arm of Takeda Pharmaceutical, holding venture stakes in therapeutics companies in oncology, cell therapy, immunology and genetic medicine.
The Engine
Cambridge, MAMIT-linked venture firm investing in tough tech companies solving the world's biggest problems across energy, health, and computing.
Third Rock Ventures
Boston, MADrug-discovery company creator incubating orphan and rare disease treatments.
Type One Ventures
Los Angeles, CAFocuses on enabling infrastructure for the space economy.
UPMC Enterprises
Pittsburgh, PAUPMC Enterprises is the innovation, commercialization and venture capital arm of Pittsburgh health system UPMC, investing in and building digital health and life sciences companies from early to growth stage.
Venrock
Palo Alto, CAVenture capital firm with roots in the Rockefeller family, investing in technology and healthcare companies for over 50 years.
Venrock Healthcare
New York, NYHealthcare-focused venture arm of Venrock, the Rockefeller family venture fund, investing in biotech and digital health.
Versant Ventures
San Francisco, CACreates companies from in-house discovery labs with big-pharma discipline.
Finistere Ventures
San Diego, CAVenture capital firm investing in agtech, food tech, and biotechnology companies that address global food security and sustainability challenges. They focus on technologies that improve agricultural productivity and food system resilience.
Johnson & Johnson Innovation - JJDC
New Brunswick, NJJJDC is the venture capital arm of Johnson & Johnson, investing in breakthrough healthcare innovations across pharmaceuticals, medical devices, and consumer health. They focus on companies developing transformative solutions for patients worldwide.
Main Sequence Ventures
Sydney, AustraliaMain Sequence Ventures is a deep tech venture capital firm spun out of CSIRO, Australia's national science agency. The firm invests in startups built on breakthrough science and technology, bridging the gap between research and commercialization.
Northpond Ventures
Bethesda, MDLife sciences venture capital firm investing in biotechnology, pharmaceutical, and medical technology companies. Focuses on translating breakthrough scientific discoveries into transformational medicines and healthcare solutions.
PureTech Health
Boston, MAA clinical-stage biopharma company that discovers and develops medicines for devastating diseases. Operates a unique model combining venture creation with drug development.
Roche Venture Fund
Basel, SwitzerlandRoche's strategic investment arm focused on early-stage companies developing breakthrough healthcare technologies. Invests in innovative therapeutics, diagnostics, and digital health solutions that align with Roche's strategic priorities.
Thrive Capital
New York, NYThrive Capital is a New York venture capital firm founded by Joshua Kushner in 2009. It invests from seed through late-stage growth rounds, mostly in software, AI, fintech and frontier technology. In February 2026 it closed Thrive X at more than $10 billion, split into $1 billion for early-stage investments and $9 billion for growth-stage investments.