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🧬 VC Directory

79 Biotech VC Firms

79 venture capital firms investing in Biotech. Browse investor profiles, investment stages, check sizes and portfolio companies.

Biotech venture works differently from the rest of this directory and the list should be read on its own terms. Rounds are larger, they are milestone-driven rather than revenue-driven, the syndicate matters more than the lead's brand, and a meaningful share of these firms create companies rather than only fund them.

The dedicated life-sciences investors here include 5AM Ventures, Atlas Venture, Venrock Healthcare, PureTech Health, Hatteras Venture Partners and Flare Capital Partners. Several run a venture-creation model in which the firm's own scientists and entrepreneurs build the company around a piece of science, often before a founding team exists, which changes what a first conversation looks like: the firm is evaluating the asset and the mechanism, not a pitch.

A second group sits at the boundary between biology and computation. Andreessen Horowitz Bio + Health, Air Street Capital, Compound, AIX Ventures and Third Culture Capital back companies applying machine learning to protein design, target identification and trial design. Playground Global and Future Ventures reach the sector through deep tech. On the agricultural and industrial side, Finistere Ventures, AgFunder and Cultivian Sandbox Ventures invest in biology applied outside human health.

Geography is concentrated. Boston and Cambridge, the Bay Area, San Diego and the Research Triangle account for most of the firms on this page, and the concentration is a function of where the research and the experienced drug-development operators are.

How to use this list. Match on modality and stage before anything else: a firm that does small molecules at Series A is not a seed investor in diagnostics, however adjacent the two look on a website. Read the portfolio and the team listing on each profile to find the partner who has run your specific development path, and expect the introduction to matter more here than in software, because these syndicates are built on long professional relationships. Each profile carries stage focus, sector focus, check size where disclosed, and fund history.

79 firms

Top Biotech firms in this list

2048 Ventures logo

2048 Ventures

New York, NY

Pre-seed firm guaranteeing funds in 10 business days.

Pre-Seed, SeedBiotech, AI, Digital Health$500K – $1.5M
3CC | Third Culture Capital logo

3CC | Third Culture Capital

Boston, MA

Learn which startups 3CC | Third Culture Capital invests in, what size check sizes they write, and who their partners are (e.g. Julien Pham).

Pre-Seed, Seed, Series A, Series B+Digital Health, Biotech, AI$250K – $1M
5AM Ventures logo

5AM Ventures

San Francisco, CA

Early-stage life sciences with 4:59 Initiative model.

Seed, Series ABiotech, Digital Health$100K – $5M
8VC logo

8VC

Austin, TX

Acts as VC and venture studio co-founding startups with 25-30% capital allocation.

Pre-Seed, Seed, Series A, Series B+Enterprise, Biotech, Digital Health$500K – $50M
AIX Ventures logo

AIX Ventures

San Francisco, CA

Led by active AI practitioners Socher, Manning, Goldbloom.

Pre-Seed, SeedAI, Biotech, Digital Health$100K – $1M
ARCH Venture Partners logo

ARCH Venture Partners

Chicago, IL

Invests at concept stage, co-founding breakthrough life sciences platforms.

Seed, Series ABiotech, Digital Health$500K – $5M
A

AbbVie Ventures

Cambridge, MA

AbbVie Ventures is the strategic venture capital arm of AbbVie, investing mainly at Seed and Series A in discovery and preclinical therapeutics companies aligned with AbbVie's R&D areas.

Seed, Series A, Series B+Biotech
Acequia Capital (AceCap) logo

Acequia Capital (AceCap)

Seattle, WA

Learn which startups Acequia Capital (AceCap) invests in, what size check sizes they write, and who their partners are (e.g. Hank Vigil).

Pre-Seed, Seed, Series A, Series B+AI, Biotech, Enterprise$100K – $5M
Acre Venture Partners logo

Acre Venture Partners

San Francisco, CA

Climate-focused agrifood fund with rare food-policy expertise

Seed, Series B+Agriculture, Climate, Biotech$100K – $10M
AgFunder logo

AgFunder

San Francisco, CA

Learn which startups AgFunder invests in, what size check sizes they write, and who their partners are (e.g. Michael Dean).

Pre-Seed, Seed, Series A, Series B+Agriculture, Biotech, Climate$10K – $5M
Air Street Capital logo

Air Street Capital

London, UK

Focuses exclusively on AI-first companies in technical domains.

Seed, Series AAI, Biotech, Enterprise$100K – $5M
A

Alexandria Venture Investments

Pasadena, California

Alexandria Venture Investments is the strategic venture arm of life science REIT Alexandria Real Estate Equities, backing seed, early and growth-stage biotech, agrifoodtech and climate companies since 1996.

Seed, Series A, Series B+Biotech, Agriculture, Climate
A

Amgen Ventures

Thousand Oaks, CA

Amgen Ventures is the strategic venture arm of Amgen, investing since 2004 in private biotechnology companies and venture funds aligned with Amgen's research priorities in oncology, inflammation and other areas.

Seed, Series A, Series B+Biotech, Digital Health
Andreessen Horowitz logo

Andreessen Horowitz

Menlo Park, CA

Leads mega-rounds for frontier-tech visions with 150+ platform team and media operations.

Seed, Series A, Series B+AI, Biotech, Deeptech$500K – $100M
Andreessen Horowitz Bio + Health logo

Andreessen Horowitz Bio + Health

Menlo Park, CA

Dedicated bio and health fund within a16z, investing in founders applying engineering and computational approaches to biology and healthcare.

Seed, Series A, Series B+Biotech, Digital Health, AI$2M – $100M
A

Angelini Ventures

Rome, Italy

Angelini Ventures is the Rome-based venture capital firm of Angelini Industries, investing a €300 million commitment in biotech and healthtech companies across Europe and North America.

Seed, Series A, Series B+Biotech, Digital Health
A

Applied Ventures

Santa Clara, California

Applied Ventures is the Santa Clara venture capital arm of Applied Materials, a stage-agnostic deep tech investor in semiconductors, photonics, AI hardware, advanced materials and robotics startups.

Seed, Series A, Series B+Deeptech, AI, Robotics
Artis Ventures (AV) logo

Artis Ventures (AV)

San Francisco, CA

Learn which startups Artis Ventures (AV) invests in, what size check sizes they write, and who their partners are (e.g. Stuart Peterson).

Pre-Seed, Seed, Series A, Series B+Digital Health, Biotech, Deeptech$50K – $25M
Atlas Venture logo

Atlas Venture

Cambridge, MA

Seed and early-stage investor emphasizing biotech company creation.

Seed, Series ABiotech$500K – $1M
Canaan Partners logo

Canaan Partners

Westport, CT

Deliberate 60/40 tech/healthcare split with transparent partner scoring.

Seed, Series ABiotech, Enterprise, Consumer$1M – $20M
Carbon Silicon Ventures logo

Carbon Silicon Ventures

Learn which startups Carbon Silicon Ventures invests in, what size check sizes they write, and who their partners are (e.g. Nish Bhat).

Pre-Seed, Seed, Series A, Series B+Biotech, Deeptech$100K – $500K
Civilization Ventures logo

Civilization Ventures

Tiburon, CA

Learn which startups Civilization Ventures invests in, what size check sizes they write, and who their partners are (e.g. Shahram Seyedin-Noor).

Pre-Seed, Seed, Series A, Series B+Digital Health, Biotech$100K – $10M
Compound logo

Compound

San Francisco, CA

Contrarian n-of-1 investor across frontier sectors.

Seed, Series AAI, Biotech$400K – $1.5M
Contrary logo

Contrary

San Francisco, CA

Venture firm powered by a network of top university students and recent graduates, scouting and investing in the next generation of founders.

Pre-Seed, Seed, Series AAI, Enterprise, Consumer$100K – $15M
Correlation Ventures logo

Correlation Ventures

San Diego, CA

Analytics-driven co-investor making rapid decisions using proprietary model.

Seed, Series A, Series B+Enterprise, Consumer, Biotech$100K – $4M
Cultivian Sandbox Ventures logo

Cultivian Sandbox Ventures

Chicago, IL

Learn which startups Cultivian Sandbox Ventures invests in, what size check sizes they write, and who their partners are (e.g. Steve Engelberg).

Pre-Seed, Seed, Series A, Series B+Agriculture, Biotech, Climate$1M – $10M
DCVC logo

DCVC

San Francisco, CA

Targets companies applying modern computation to agriculture, mining, and health.

Seed, Series ADeeptech, Biotech, Climate$5M – $25M
Decheng Capital

Decheng Capital

Menlo Park, CA

Learn which startups Decheng Capital invests in, what size check sizes they write, and who their partners are (e.g. ).

Pre-Seed, Seed, Series A, Series B+Biotech, Digital Health$. – $.
Dolby Family Ventures logo

Dolby Family Ventures

San Francisco, CA

Learn which startups Dolby Family Ventures invests in, what size check sizes they write, and who their partners are (e.g. Pascal Levensohn).

Pre-Seed, Seed, Series A, Series B+Biotech, Digital Health, Climate$. – $.
E1 Ventures logo

E1 Ventures

Learn which startups E1 Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).

Pre-Seed, Seed, Series A, Series B+AI, Aerospace & Defense, Robotics$. – $.
E2MC Ventures logo

E2MC Ventures

Los Angeles, CA

E2MC Ventures is a Los Angeles-based early-stage venture firm specializing in the space economy, investing in satellite technology, launch services, in-space manufacturing, and the broader ecosystem of technologies enabling a multi-planetary future. The firm focuses on pre-seed and seed stage companies where its deep aerospace network and technical expertise provide the most leverage. E2MC backs founders building infrastructure for the commercial space industry and adjacent deep tech sectors.

Seed, Series ASpace, Biotech$500K – $2M
F-Prime Capital logo

F-Prime Capital

Cambridge, MA

Fidelity-backed formation engine for gene therapy and rare diseases.

Seed, Series A, Series B+Biotech, Digital Health$100K – $10M
FPV Ventures logo

FPV Ventures

San Francisco, CA

Learn which startups FPV Ventures invests in, what size check sizes they write, and who their partners are (e.g. Pegah Ebrahimi).

Pre-Seed, Seed, Series A, Series B+Enterprise, Consumer, Biotech$100K – $5M
FemHealth Ventures logo

FemHealth Ventures

Short Hills, NJ

Learn which startups FemHealth Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).

Pre-Seed, Seed, Series A, Series B+Digital Health, Biotech$. – $.
Fifty Years logo

Fifty Years

San Francisco, CA

Operator-heavy team backing pre-product deep-tech moonshots.

Pre-Seed, SeedBiotech, Digital Health, Deeptech$250K – $2M
Flagship Pioneering logo

Flagship Pioneering

Cambridge, MA

Learn which startups Flagship Pioneering invests in, what size check sizes they write, and who their partners are (e.g. Noubar Afeyan).

Pre-Seed, Seed, Series A, Series B+Biotech, Digital Health, Agriculture$. – $.
Flare Capital Partners logo

Flare Capital Partners

Boston, MA

Learn which startups Flare Capital Partners invests in, what size check sizes they write, and who their partners are (e.g. Bill Geary).

Pre-Seed, Seed, Series A, Series B+Digital Health, Biotech$1M – $10M
Founders Fund logo

Founders Fund

San Francisco, CA

Contrarian, founder-maximalist VC backing hard scientific breakthroughs.

Seed, Series A, Series B+AI, Biotech, Aerospace & Defense$500K – $150M
FundersClub logo

FundersClub

San Francisco, CA

Learn which startups FundersClub invests in, what size check sizes they write, and who their partners are (e.g. ).

Pre-Seed, Seed, Series A, Series B+Enterprise, DevTools, Consumer$. – $.
Future Ventures logo

Future Ventures

San Francisco, CA

Invests in purpose-driven entrepreneurs reinventing industries.

Pre-Seed, Seed, Series ABiotech, Deeptech, AI$1M – $10M
GV logo

GV

Mountain View, CA

Google's financially-driven VC with design studio and ML scoring.

Seed, Series A, Series B+AI, Biotech, Consumer$250K – $50M
Genoa Ventures logo

Genoa Ventures

San Francisco, CA

Learn which startups Genoa Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).

Pre-Seed, Seed, Series A, Series B+Biotech, Digital Health, Deeptech$. – $.
Hatteras Venture Partners

Hatteras Venture Partners

Durham, NC

Learn which startups Hatteras Venture Partners invests in, what size check sizes they write, and who their partners are (e.g. ).

Pre-Seed, Seed, Series A, Series B+Biotech, Digital Health$. – $.
Innovation Endeavors logo

Innovation Endeavors

Palo Alto, CA

Founded by Eric Schmidt; invests in sensors, ML, and robotics.

Seed, Series AAI, Deeptech, Biotech$1M – $15M
Julian Capital logo

Julian Capital

San Francisco, CA

Deeptech seed fund investing across chips, chemicals, energy, robotics.

Pre-Seed, SeedDeeptech, Robotics, Biotech$750K – $750K
K

Kaiser Permanente Ventures

Oakland, CA

Kaiser Permanente Ventures is the strategic venture arm of Kaiser Permanente, investing in healthcare IT, care delivery services, diagnostics and therapeutics companies that address needs in healthcare delivery.

Series A, Series B+Digital Health, Biotech, AI
KittyHawk Ventures logo

KittyHawk Ventures

Santa Monica, CA

KittyHawk Ventures is a New York-based venture firm that invests across the capital stack, from frontier seed rounds all the way through pre-IPO growth equity, focusing on transformative technology companies in sectors including fintech, enterprise software, and aerospace. The firm takes a flexible, stage-agnostic approach that allows it to build concentrated positions in breakout companies over multiple rounds. KittyHawk is known for its long-term partnership model and willingness to back unconventional founders with bold visions.

Seed, Series A, Series B+Digital Health, Biotech, Robotics$250K – $15M
L

LG Technology Ventures

Santa Clara, CA

LG Technology Ventures is the Santa Clara venture arm of South Korea's LG Group, backing early and growth-stage companies in AI, batteries and energy, life sciences, materials and enterprise software.

Seed, Series A, Series B+AI, Climate, Biotech
L

Leaps by Bayer

Berlin, Germany

Leaps by Bayer is the strategic investment unit of Bayer AG, backing and forming companies that pursue fundamental breakthroughs in health and agriculture across ten defined challenges.

Seed, Series A, Series B+Biotech, Agriculture, Digital Health
L

Lilly Ventures

Indianapolis, IN

Lilly Ventures is Eli Lilly's global investment arm, formed in 2001, investing in early-stage biotech and novel science as one pillar of the Lilly Catalyze360 program for young drug developers.

Seed, Series A, Series B+Biotech, Digital Health
Lux Capital logo

Lux Capital

New York, NY

Deep technology venture firm investing in emerging science and technology ventures in energy, healthcare, and defense.

Seed, Series A, Series B+Deeptech, Aerospace & Defense, AI$1M – $50M
Maverick Ventures logo

Maverick Ventures

San Francisco, CA

Evergreen fund integrated with $10B+ hedge-fund platform.

Seed, Series A, Series B+Digital Health, AI, Biotech$3M – $10M
NFX logo

NFX

San Francisco, CA

Serial founder-led with Signal platform and CEO Guild network.

Pre-Seed, SeedAI, Biotech, Marketplace$500K – $5M
N

Novartis Venture Fund

Basel, Switzerland

The Novartis Venture Fund is the corporate venture arm of Novartis, investing USD 5 to 10 million at seed and Series A in therapeutics companies across North America and Europe.

Seed, Series ABiotech$5M – $10M
OrbiMed Advisors logo

OrbiMed Advisors

New York, NY

Healthcare-only platform spanning seed through IPO via public/private arms.

Series A, Series B+Biotech, Digital Health$1M – $75M
P

Pfizer Ventures

New York, NY

Pfizer Ventures is the venture capital arm of Pfizer, investing in biotech companies in oncology, inflammation and immunology, cardiometabolic disease, vaccines and next-generation modalities.

Seed, Series A, Series B+Biotech$10M
Pillar VC logo

Pillar VC

Boston, MA

Boston seed investor supporting professional growth.

Pre-Seed, Seed, Series ABiotech, Deeptech, Enterprise$100K – $10M
Playground Global logo

Playground Global

Palo Alto, CA

Deep technology venture fund investing in AI, robotics, and synthetic biology startups with transformative potential.

Seed, Series AAI, Robotics, Deeptech$1M – $15M
Polaris Partners logo

Polaris Partners

Boston, MA

Polaris Partners is a Boston venture capital firm founded in 1996 that invests mainly in biotechnology and healthcare companies, from company creation through later rounds. It has more than $5 billion in committed capital and runs two affiliated vehicles: the Polaris Innovation Fund for academic research and the Polaris Growth Fund for profitable, founder-owned software companies.

Seed, Series A, Series B+Biotech, Digital Health, SaaS$1M – $50M
Prime Movers Lab logo

Prime Movers Lab

Jackson, WY

Deep tech venture firm investing in breakthrough scientific startups across energy, transportation, infrastructure, and health.

Seed, Series ADeeptech, Climate, Space$500K – $15M
Radical Ventures logo

Radical Ventures

Toronto, Canada

Invests in very-early to early-stage AI startups with AI research ties.

Pre-Seed, Seed, Series AAI, Digital Health, Biotech$1M – $25M
Refactor Capital logo

Refactor Capital

Burlingame, CA

Solo GP leveraging Google/Netflix/LinkedIn experience to back hard-tech.

Seed, Series A, Series B+Biotech, Digital Health, Climate$100K – $1.5M
S32 (formerly Section 32)

S32 (formerly Section 32)

Palo Alto, CA

S32, originally named Section 32, is a Palo Alto venture capital firm founded by Bill Maris, who started GV (Google Ventures) and ran it as CEO. S32 invests mainly at Series A and Series B in AI, computational biology, infrastructure, cybersecurity and enterprise software, manages more than $3 billion, and held a $413.5 million first close on its sixth fund in September 2025.

Series A, Series B+AI, Biotech, Cybersecurity$5M – $10M
S

Sanofi Ventures

Cambridge, MA

Sanofi Ventures is the corporate venture arm of Sanofi, investing from seed to crossover in biotech and AI and digital health companies from an evergreen fund of more than $1.4 billion.

Seed, Series A, Series B+Biotech, Digital Health, AI
T

Takeda Ventures

Cambridge, Massachusetts

Takeda Ventures, Inc. is the corporate investment arm of Takeda Pharmaceutical, holding venture stakes in therapeutics companies in oncology, cell therapy, immunology and genetic medicine.

Series A, Series B+Biotech
The Engine logo

The Engine

Cambridge, MA

MIT-linked venture firm investing in tough tech companies solving the world's biggest problems across energy, health, and computing.

Seed, Series ADeeptech, Climate, Biotech$500K – $10M
Third Rock Ventures logo

Third Rock Ventures

Boston, MA

Drug-discovery company creator incubating orphan and rare disease treatments.

Seed, Series ABiotech$100K – $5M
Type One Ventures

Type One Ventures

Los Angeles, CA

Focuses on enabling infrastructure for the space economy.

Pre-Seed, Seed, Series A, Series B+Space, Biotech$100K – $5M
U

UPMC Enterprises

Pittsburgh, PA

UPMC Enterprises is the innovation, commercialization and venture capital arm of Pittsburgh health system UPMC, investing in and building digital health and life sciences companies from early to growth stage.

Seed, Series A, Series B+Digital Health, Biotech, AI
Venrock logo

Venrock

Palo Alto, CA

Venture capital firm with roots in the Rockefeller family, investing in technology and healthcare companies for over 50 years.

Seed, Series AEnterprise, Digital Health, Biotech$500K – $20M
Venrock Healthcare logo

Venrock Healthcare

New York, NY

Healthcare-focused venture arm of Venrock, the Rockefeller family venture fund, investing in biotech and digital health.

Seed, Series A, Series B+Biotech, Digital Health$1M – $30M
Versant Ventures logo

Versant Ventures

San Francisco, CA

Creates companies from in-house discovery labs with big-pharma discipline.

Series ABiotech$100K – $5M
Finistere Ventures logo

Finistere Ventures

San Diego, CA

Venture capital firm investing in agtech, food tech, and biotechnology companies that address global food security and sustainability challenges. They focus on technologies that improve agricultural productivity and food system resilience.

Seed, Series A, Series B+Agriculture, Biotech, Climate$1M – $20M
Johnson & Johnson Innovation - JJDC

Johnson & Johnson Innovation - JJDC

New Brunswick, NJ

JJDC is the venture capital arm of Johnson & Johnson, investing in breakthrough healthcare innovations across pharmaceuticals, medical devices, and consumer health. They focus on companies developing transformative solutions for patients worldwide.

Series A, Series B+Digital Health, Biotech, AI$3M – $75M
Main Sequence Ventures

Main Sequence Ventures

Sydney, Australia

Main Sequence Ventures is a deep tech venture capital firm spun out of CSIRO, Australia's national science agency. The firm invests in startups built on breakthrough science and technology, bridging the gap between research and commercialization.

Pre-Seed, Seed, Series ADeeptech, AI, Climate$500K – $10M
Northpond Ventures logo

Northpond Ventures

Bethesda, MD

Life sciences venture capital firm investing in biotechnology, pharmaceutical, and medical technology companies. Focuses on translating breakthrough scientific discoveries into transformational medicines and healthcare solutions.

Seed, Series A, Series B+Biotech, Digital Health$2M – $25M
PureTech Health

PureTech Health

Boston, MA

A clinical-stage biopharma company that discovers and develops medicines for devastating diseases. Operates a unique model combining venture creation with drug development.

Seed, Series A, Series B+Biotech, Digital Health
Roche Venture Fund logo

Roche Venture Fund

Basel, Switzerland

Roche's strategic investment arm focused on early-stage companies developing breakthrough healthcare technologies. Invests in innovative therapeutics, diagnostics, and digital health solutions that align with Roche's strategic priorities.

Series A, Series B+Biotech, Digital Health$5M – $30M
Thrive Capital logo

Thrive Capital

New York, NY

Thrive Capital is a New York venture capital firm founded by Joshua Kushner in 2009. It invests from seed through late-stage growth rounds, mostly in software, AI, fintech and frontier technology. In February 2026 it closed Thrive X at more than $10 billion, split into $1 billion for early-stage investments and $9 billion for growth-stage investments.

Seed, Series A, Series B+AI, Enterprise, Fintech$5M – $100M