Skip to main content

At a Glance

Check Size
$. – $.
Stage
Pre-Seed, Seed, Series A, Series B+
Sectors
Biotech, Digital Health, Deeptech
HQ
San Francisco, CA

About Genoa Ventures

Genoa Ventures is a San Francisco, California venture firm that invests where biology and technology converge. Founded and led by Jenny Rooke, the firm backs companies whose products depend on advances in both the life sciences and engineering, on the view that this convergence is where the pace of innovation can be accelerated and whole industries reshaped. Genoa describes its work as identifying those opportunities early and then concentrating capital and operating expertise behind them, with the stated aim of helping build category-defining companies that make the world healthier, cleaner and more productive. Its stated sequence is converge, focus, launch and empower. The founding principle of the firm is to improve the performance and stability of its portfolio companies on the way to their full potential, and the team is assembled with that in mind: its backgrounds span investing, company operating roles, scientific research and discovery, and launching and scaling businesses across both the biology and technology sectors. Genoa positions itself as an extension of the company team rather than a passive shareholder, describing itself as part of the extended team once it invests, and it works with a set of strategic partners alongside its own staff. The firm publishes commentary from the frontlines of biology and technology, including on human genomics and next-generation clinical assessment tools, and Rooke is a recurring presenter at the J.P. Morgan Healthcare Conference. For founders, Genoa is most relevant when a company sits at the boundary of a life-science insight and a technology platform and needs an investor fluent in both, rather than a generalist technology fund or a pure therapeutics investor.

Leadership Team

Jenny Rooke founded Genoa Ventures and is named as the member of the general partner entity on every fund the firm has filed, from Genoa Ventures GP II, LLC through GP III, which makes her the signing principal on the platform's capital as well as its public voice. She is the firm's advocate for the thesis that biology and technology have converged into one investable category rather than two adjacent ones.

Roughly a dozen investors and operators are listed on the firm's team page working alongside her. Genoa does not publish full names, titles, prior roles or education for that wider bench at a crawlable address, so their backgrounds are not documented here. Investor and management-team contact runs directly through Rooke rather than through a general inbox.

Sector Focus

Investment Stage

Fund History

Genoa Ventures has raised three institutional funds and one single-deal vehicle since 2018. Genoa Ventures Fund I, LP entered exempt-offering records that year. Fund II, LP recorded its first sale on 29 January 2021 and reported $56.68 million raised from 95 accredited investors against an indefinite offering; a parallel vehicle, Genoa Ventures Fund II-A, LP, registered later in 2021 to run alongside it.

Fund III, LP filed its Form D in June 2024, again on an indefinite offering, with no sales recorded at the time of filing. In 2025 the firm added Genoa Ventures SPV LLC Series 1, a Delaware vehicle for concentrating limited partner capital into a single company outside the fund structure. Jenny Rooke is named as the member of the general partner on each fund. Total committed capital across the platform is not disclosed, and the filings report indefinite offering amounts rather than target fund sizes.

Frequently Asked Questions

What stage does Genoa Ventures invest at?

Genoa Ventures primarily invests at the Pre-Seed, Seed, Series A, Series B+ stages. This means they focus on companies that are at the earliest idea or prototype phase.

Where is Genoa Ventures located?

Genoa Ventures is headquartered in San Francisco, CA. Many of their portfolio companies are also based in this region, though they invest across geographies.

What sectors does Genoa Ventures focus on?

Genoa Ventures focuses on investments in Biotech, Digital Health, Deeptech. Their portfolio reflects deep expertise and networks within these sectors.

What is Genoa Ventures's typical check size?

Genoa Ventures's typical investment check size ranges from $. to $.. Actual amounts may vary based on the stage, sector, and specific opportunity.

Fund Operations Resources

Running a fund like Genoa Ventures? Independent guides to the software and processes emerging managers use to operate.

Sponsored
AArchstone

The operating system for private capital.

Archstone runs the back office for venture, PE, real estate, and credit funds — LP reporting, capital calls, portfolio tracking, and fund accounting, in one platform. Now in alpha.

LP portalCapital calls$297/moNo AUM fees
Book a demo