
F-Prime Capital
UnclaimedAt a Glance
- Check Size
- $100K – $10M
- Stage
- Seed, Series A, Series B+
- AUM
- $4B
- Sectors
- Biotech, Digital Health
- Founded
- 1999
- HQ
- Cambridge, MA
About F-Prime Capital
F-Prime Capital is a venture capital firm based in Cambridge, MA founded in 1999. F-Prime Capital is a global venture capital firm investing in life sciences, technology healthtech + services, and crypto, with a heritage that spans four decades. The firm focuses on Seed, Series A, Series B+ investments across sectors including Biotech, Digital Health. The firm manages $4B in assets under management. Notable portfolio companies include Discord, Ro, Veracyte, Flatiron Health, Quartet Health, Mindstrong and Alto Pharmacy. Healthcare and technology investor focusing on companies that improve human health and transform industries through data and technology.
Investment Thesis
“Healthcare and technology investor focusing on companies that improve human health and transform industries through data and technology.”
Leadership Team
F-Prime's bench is unusually deep for a venture firm, with more than 130 people listed across investment, venture network and operations teams and four sector groups covering healthtech and services, technology, life sciences and crypto.
Alex Pasteur, a Partner based in London, has invested in therapeutics and life sciences at the firm since 2012 and was a founding investor in ARTBIO, Tenpoint Therapeutics and Orchard Therapeutics, which Kyowa Kirin acquired. He came from MVM Life Science Partners and holds an MA in natural sciences and a PhD in chemistry from Cambridge. Gaurav Tuli, a Partner in Cambridge, covers enterprise technology and led investments in Threat Stack, acquired by F5 Networks, RiskRecon, acquired by Mastercard, and Protenus. He was previously a Principal at Eight Roads Ventures Europe and worked at EMC, Credit Suisse and McKinsey, with bachelor's, master's and MBA degrees from MIT.
Sector Focus
Investment Stage
Notable Portfolio Companies
Fund History
F-Prime does not raise capital through public private placements. A search of SEC Form D filings returns no offerings under the F-Prime Capital name, consistent with a manager funded through Fidelity-affiliated structures rather than third-party limited partners. That absence of an LP fundraising trail is the defining structural fact about the firm and separates it from conventional venture managers of comparable scale, since there are no fund vintages, closes or investor counts on the public record to track.
F-Prime states that its portfolio list includes investments made by Fidelity Ventures and Eight Roads, the predecessor and sister vehicles its heritage runs through, and that since July 1, 2024 it also advises Fine Structure Ventures. The firm invests across life sciences, technology, healthtech and services, and crypto, operating from Cambridge, Massachusetts, London and San Francisco. Disclosed positions include Beam Therapeutics, Toast, Equip, Flywire, Devoted Health, Denali Therapeutics, Benchling and Iora Health.
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Frequently Asked Questions
What stage does F-Prime Capital invest at?
F-Prime Capital primarily invests at the Seed, Series A, Series B+ stages. This means they focus on companies that are building their initial product and finding product-market fit.
Where is F-Prime Capital located?
F-Prime Capital is headquartered in Cambridge, MA. Many of their portfolio companies are also based in this region, though they invest across geographies.
What sectors does F-Prime Capital focus on?
F-Prime Capital focuses on investments in Biotech, Digital Health. Their portfolio reflects deep expertise and networks within these sectors.
What is F-Prime Capital's typical check size?
F-Prime Capital's typical investment check size ranges from $100K to $10M. Actual amounts may vary based on the stage, sector, and specific opportunity.
How much does F-Prime Capital have under management?
F-Prime Capital manages approximately $4B in assets under management (AUM) across their funds.
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