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At a Glance

Check Size
$. – $.
Stage
Pre-Seed, Seed, Series A, Series B+
AUM
$7.2B
Sectors
Biotech, Digital Health, Agriculture +1
Founded
2000
HQ
Cambridge, MA

About Flagship Pioneering

Flagship Pioneering is a venture capital firm based in Cambridge, MA founded in 2000. Pioneering Partnerships Latest News Companies founded 120+ The firm focuses on Pre-Seed, Seed, Series A, Series B+ investments across sectors including Aerospace & Defense, Digital Health, Other, Consumer, Fintech. The firm manages $7.2B in assets under management. Notable portfolio companies include Moderna, Indigo Agriculture, Evelo Biosciences, Generate Biomedicines, Sana Biotechnology, Tessera Therapeutics, Ring Therapeutics and Pioneering Medicines. Creates and funds breakthrough life sciences companies through venture creation model, focusing on transformative innovations in health, sustainability, and human potential.

Investment Thesis

“Creates and funds breakthrough life sciences companies through venture creation model, focusing on transformative innovations in health, sustainability, and human potential.”

Sector Focus

Investment Stage

Notable Portfolio Companies

ModernaModerna
IIndigo Agriculture
Evelo BiosciencesEvelo Biosciences
GGenerate Biomedicines
SSana Biotechnology
TTessera Therapeutics
RRing Therapeutics
PPioneering Medicines

Fund History

  • Flagship's fund line runs continuously from 2010 and shows one of the steepest escalations in life sciences venture.
  • Flagship Ventures Fund IV filed in November 2010 on a $250 million offering, with $136.75 million sold to 14 investors by November 2011 against a first sale of November 5, 2010.
  • Fund V filed in December 2014 at $350 million, the last vintage raised under the Flagship Ventures name.
  • The firm then rebranded: Flagship Pioneering Fund VI filed in September 2017 on a $500 million target and closed fully sold at $618 million across 44 investors.
  • Fund VII, originally registered in March 2020 as Flagship Pioneering - Origination Fund VII at a $1.1 billion target, closed at $2,131,240,000 fully sold to 97 investors with a first sale of May 28, 2021.
  • Fund VIII filed in November 2023 targeting $3 billion and closed at $2,590,563,688 across 109 investors.
  • Flagship Ventures Opportunities Fund I and Special Opportunities Fund II sit alongside the flagship line.
  • Noubar Afeyan signs every filing from Fund V onward as executive officer.

Team (6)

Related Articles (3)

Frequently Asked Questions

What stage does Flagship Pioneering invest at?

Flagship Pioneering primarily invests at the Pre-Seed, Seed, Series A, Series B+ stages. This means they focus on companies that are at the earliest idea or prototype phase.

Where is Flagship Pioneering located?

Flagship Pioneering is headquartered in Cambridge, MA. Many of their portfolio companies are also based in this region, though they invest across geographies.

What sectors does Flagship Pioneering focus on?

Flagship Pioneering focuses on investments in Biotech, Digital Health, Agriculture, Climate. Their portfolio reflects deep expertise and networks within these sectors.

What is Flagship Pioneering's typical check size?

Flagship Pioneering's typical investment check size ranges from $. to $.. Actual amounts may vary based on the stage, sector, and specific opportunity.

How much does Flagship Pioneering have under management?

Flagship Pioneering manages approximately $7.2B in assets under management (AUM) across their funds.

Fund Operations Resources

Running a fund like Flagship Pioneering? Independent guides to the software and processes emerging managers use to operate.

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