VC Directory

Venture Capital Firms in Cambridge, MA

9 venture capital firms headquartered in Cambridge, MA. Browse investor profiles, investment stages, and sector focus areas.

Top firms in Cambridge, MA

Azolla Ventures · Pre-Seed to Series B+ · Climate
F-Prime Capital · Seed to Series B+ · Biotech
Flagship Pioneering · Pre-Seed to Series B+ · Biotech
Founder Collective · Pre-Seed to Series B+ · Consumer
General Catalyst · Seed to Series B+ · Digital Health
The Engine · Seed to Series A · Deeptech

Atlas Venture

Seed and early-stage investor emphasizing biotech company creation.

Seed, Series ABiotech$500K – $1M

Azolla Ventures

Learn which startups Azolla Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).

Pre-Seed, Seed, Series A, Series B+Climate$. – $.

Castle Island Ventures

Learn which startups Castle Island Ventures invests in, what size check sizes they write, and who their partners are (e.g. Matthew Walsh).

Pre-Seed, Seed, Series A, Series B+Aerospace & Defense, Other, Consumer$100K – $5M

F-Prime Capital

Fidelity-backed formation engine for gene therapy and rare diseases.

Seed, Series A, Series B+Biotech, Digital Health$100K – $10M

Flagship Pioneering

Learn which startups Flagship Pioneering invests in, what size check sizes they write, and who their partners are (e.g. Noubar Afeyan).

Pre-Seed, Seed, Series A, Series B+Biotech, Digital Health, Agriculture$. – $.

Founder Collective

Learn which startups Founder Collective invests in, what size check sizes they write, and who their partners are (e.g. Eric Paley).

Pre-Seed, Seed, Series A, Series B+Consumer, Marketplace, Enterprise$. – $.

General Catalyst

Hatch-heritage company builder with AI transformation platforms.

Seed, Series A, Series B+Digital Health, Fintech, Enterprise$500K – $100M

GreatPoint Ventures

Learn which startups GreatPoint Ventures invests in, what size check sizes they write, and who their partners are (e.g. Andrew Perlman).

Pre-Seed, Seed, Series A, Series B+Aerospace & Defense, Digital Health, Other$3M – $10M

The Engine

MIT-linked venture firm investing in tough tech companies solving the world's biggest problems across energy, health, and computing.

Seed, Series ADeeptech, Climate, Biotech$500K – $10M

Frequently Asked Questions

What are the best VC firms in Cambridge, MA?

Cambridge, MA is home to 9+ active venture capital firms. The top firms in the area are known for strong local networks, deep deal flow, and specialized sector expertise that benefits from the Cambridge, MA ecosystem.

How many VC firms are based in Cambridge, MA?

There are 9+ venture capital firms actively investing from Cambridge, MA. This includes seed-stage funds, growth equity firms, and multi-stage investors with offices in the metro area.

Do I need to be based in Cambridge, MA to get funded by local VCs?

No — while Cambridge, MA-based VCs historically preferred local companies, most now invest nationally and even globally. However, being local can help with building relationships and accessing the firm's network of portfolio companies and advisors.