Define Ventures
UnclaimedAt a Glance
- Check Size
- $750K – $6M
- Stage
- Pre-Seed, Seed, Series A, Series B+
- AUM
- $300M
- Sectors
- Aerospace & Defense, Digital Health, Other +2
- Founded
- 2016
- HQ
- San Francisco, CA
About Define Ventures
Define Ventures is a venture capital firm based in San Francisco, CA founded in 2016. Define Ventures is one of the largest funds focused on early-stage digital health companies. Our founders choose us because we play offense and drive results. The firm focuses on Pre-Seed, Seed, Series A, Series B+ investments across sectors including Aerospace & Defense, Digital Health, Other, Consumer, Fintech. Notable portfolio companies include Curology, Grail, Clubhouse, NotCo and Sword Health. Invests in early-stage companies building transformative technologies across health, fintech, consumer, and frontier tech sectors.
Investment Thesis
“Invests in early-stage companies building transformative technologies across health, fintech, consumer, and frontier tech sectors.”
Sector Focus
Investment Stage
Notable Portfolio Companies
View full portfolio →Fund History
Define Ventures has raised every vehicle from a San Francisco base since 2018. Fund I, L.P. closed at $87,575,757, fully subscribed against its offering, following a first sale on October 16, 2018. Fund II, L.P. followed two years later, filing a $200 million offering that was also fully sold after a first sale on October 16, 2020. A dedicated later-stage vehicle, Define Ventures Opportunities I, L.P., raised $30 million in April 2021. In July 2022 the firm filed twin Regulation D notices for Define Ventures Fund III, L.P. and Define Ventures Opportunities II/III, L.P., each carrying a $425 million offering amount, by far the largest capital raise in the firm's history and a step change from the Fund II vintage. A smaller vehicle, Define Ventures Select I, L.P., was filed in February 2024 with a $6.2 million offering. Each fund is managed through a matching Define Ventures GP entity, with Lynne Chou O'Keefe signing as the control person on every filing.
Team (1)
Related Articles (6)
Frequently Asked Questions
What stage does Define Ventures invest at?
Define Ventures primarily invests at the Pre-Seed, Seed, Series A, Series B+ stages. This means they focus on companies that are at the earliest idea or prototype phase.
Where is Define Ventures located?
Define Ventures is headquartered in San Francisco, CA. Many of their portfolio companies are also based in this region, though they invest across geographies.
What sectors does Define Ventures focus on?
Define Ventures focuses on investments in Aerospace & Defense, Digital Health, Other, Consumer, Fintech. Their portfolio reflects deep expertise and networks within these sectors.
What is Define Ventures's typical check size?
Define Ventures's typical investment check size ranges from $750K to $6M. Actual amounts may vary based on the stage, sector, and specific opportunity.
How much does Define Ventures have under management?
Define Ventures manages approximately $300M in assets under management (AUM) across their funds.
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