VC Directory
Venture Capital Firms in St. Louis, MO
4 venture capital firms headquartered in St. Louis, MO. Browse investor profiles, investment stages, and sector focus areas.
Top firms in St. Louis, MO
- Ascension Ventures · Pre-Seed to Series B+ · Aerospace & Defense
- Lewis & Clark Ventures · Seed to Series A · Enterprise
- Gateway Capital Partners · Pre-Seed to Series B+ · Aerospace & Defense
Ascension Ventures
Learn which startups Ascension Ventures invests in, what size check sizes they write, and who their partners are (e.g. ).
Cultivation Capital
Learn which startups Cultivation Capital invests in, what size check sizes they write, and who their partners are (e.g. Brian Matthews).
Gateway Capital Partners
Learn which startups Gateway Capital Partners invests in, what size check sizes they write, and who their partners are (e.g. Dana Guthrie).
Lewis & Clark Ventures
Heartland venture firm based in St. Louis investing in enterprise technology companies across the Midwest.
Frequently Asked Questions
What are the best VC firms in St. Louis, MO?
St. Louis, MO is home to 4+ active venture capital firms. The top firms in the area are known for strong local networks, deep deal flow, and specialized sector expertise that benefits from the St. Louis, MO ecosystem.
How many VC firms are based in St. Louis, MO?
There are 4+ venture capital firms actively investing from St. Louis, MO. This includes seed-stage funds, growth equity firms, and multi-stage investors with offices in the metro area.
Do I need to be based in St. Louis, MO to get funded by local VCs?
No — while St. Louis, MO-based VCs historically preferred local companies, most now invest nationally and even globally. However, being local can help with building relationships and accessing the firm's network of portfolio companies and advisors.